Nebivolol belongs to a class of drugs known as beta-blockers that treat high blood pressure. It works by selectively blocking beta-1 adrenergic receptors primarily located in the heart. This results in a decrease in heart rate and cardiac output, which can help to lower blood pressure.

In addition to its blood pressure-lowering effects, Nebivolol has also been shown to improve the ability of blood vessels to dilate and constrict and may have antioxidant and anti-inflammatory properties.